The first genetic ointment for the treatment of hereditary skin diseases
Washington: The world’s first ointment in the form of a burn has been developed which could be useful in the genetic condition of the previously declared incurable skin.
Some people suffer from dystrophic epidermolysis bellosa (EB) disease with the recessive gene. In this disease, boils appear all over the body and cannot be cured. This condition can now be cured by applying a new collagen gene to the skin with an ointment.
This is a rare genetic condition that has been successfully treated for the first time through gene therapy. In the United States alone, one in eight million children suffers from this disorder. The skin becomes delicate and sensitive until it erupts and blisters with a minor injury. That is why the daily routines of the victims are so affected and they do not feel well.
A 22-year-old patient said that he was suffering from this disease and had sores and blisters all over his body which could not be cured in any way. This condition can cause irritation of the eyelids, back and sometimes even the throat, which can lead to frequent use of liquid food. This patient has come to America from Italy for treatment.
In such patients a collagen-activated COL7A1 is affected, which prevents the skin from becoming a normal protein. For this, the experts took a simple herpes virus and inserted the KOL Seven A1 gene in it. The virus usually causes fever blisters, also called cold sores, but experts say they have lost their ability to cause disease. When it was burned, the genes began to seep into the body.
A total of 31 children and adults received the ointment, all of whom suffered from dystrophic epidermolysis belusa. Each patient was burned at seven-day intervals. Significant effects of gene therapy came three months later. All the wounds of 71% of the patients were completely healed. Now only 20% of the people who were burned with fake medicine (Play Cebu) were cured. Most importantly, no adverse side effects were observed in any patient.
According to experts, new gene therapy can cure 95% of wounds.